Optimising Therapy to prevent avoidable hospital admissions in the multimorbid elderly


OPERAM publications

Intervention protocol: Optimising thERapy to prevent Avoidable hospital admission in the Multi-morbid elderly (OPERAM): a structured medication review with support of a computerised decision support system
EK Crowley, BTGM Sallevelt, L Huibers, KD Murphy, M Spruit, Z Shen, B Boland, A Spinewine, O Dalleur, E Moutzouri, A Löwe, M Feller, N Schwab, L Adam, I Wilting, W Knol, N Rodondi, S Byrne, D O' Mahony; BMC Health Serv Res. 2020 Mar 17;20(1):220. doi: 10.1186/s12913-020-5056-3

Rationale and design of Optimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial
L. Adam, E. Moutzouri,C. Baumgartner, A. L. Loewe, M. Feller, K. M'Rabet-Bensalah, N. Schwab, S. Hossmann, C. Schneider, S. Jegerlehner, C. Floriani, A. Limacher, K. T. Jungo, C. J. A. Huibers, S. Streit, M. Schwenkglenks, M. Spruit, A. Van Dorland, J. Donzé, P. M Kearney, Peter Jüni, D. Aujesky, P. Jansen, B. Boland, O. Dalleur, S. Byrne,W. Knol, A. Spinewine, D. O’Mahony, S. Trelle, N. Rodondi; BMJ Open 2019;9:e026769. doi:10.1136/bmjopen-2018-026769

A Lightweight API-Based Approach for Building Flexible Clinical NLP Systems 
Z. Shen, H. van Krimpen, M. Spruit. Journal of Healthcare Engineering 2019. doi.org/10.1155/2019/3435609

Identification of Behaviour Change Techniques in Deprescribing Interventions: A Systematic Review and Meta-Analysis
Christina R. Hansen, Denis O’Mahony, Patricia M. Kearney, Laura J. Sahm, Shane Cullinan, C.J.A. Huibers, Stefanie Thevelin, Anne W.S. Rutjes, Wilma Knol, Sven Streit and Stephen Byrne
British Journal of Clinical Pharmacology - August 2018

Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study
David O Riordan, Carole Elodie Aubert,  Kieran A Walsh,  Anette Van Dorland, Nicolas Rodondi,  Robert S Du Puy,  Rosalinde K E Poortvliet, Jacobijn Gussekloo, Carol Sinnott, Stephen Byrne1 Rose Galvin, J Wouter Jukema, Simon P Mooijaart, Christine Baumgartner, Vera McCarthy, Elaine K Walsh, Tinh-Hai Collet, Olaf M Dekkers, Manuel R Blum, Patricia M Kearney
BMJ Open 2018;8:e019003. doi:10.1136/bmjopen-2017-019003

International core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy
Jean-Baptiste Beuscart, Wilma Knol, Shane Cullinan, Claudio Schneider, Olivia Dalleur, Benoit Boland, Stefanie Thevelin, Paul A. F. Jansen, Denis O’Mahony, Nicolas Rodondi, Anne Spinewine
BMC Medicine201816:21

Developmant of  core outcome set for medication review in older patients with multimorbidity and polypharmacy: a study protocol
Jean-Baptiste Beuscart, Olivia Dalleur, Benoit Boland, Stefanie Thevelin, Wilma Knol, Shane Cullinan, Claudio Schneider, Denis O’Mahony, Nicolas Rodondi, Anne Spinewine
Clinical Intervention in Aging, August 2017:12  1379-1389

A systematic review of the outcomes reported in trials of medication review in older patients: the need for a core outcome set
Jean-Baptiste Beuscart , Lisa G. Pont, Stefanie Thevelin, Benoit Boland, Olivia Dalleur, Anne W., S. Rutjes, Johanna I. Westbrook and Anne Spinewine
Br J Clin Pharmacol (2017) 83 942-952 

Additional considerations are required when preparing a protocol for systematic review with multiple interventions.
Chaimani A, Caldwell DM, Tianjing L, Higgins JPT, Salanti G. 
Journal of Clinical Epidemiology. 2017;83,65-74

A comparison of 20 heterogeneity variance estimators in statistical synthesis of results from studies: A simulation study.
Petropoulou M, Mavridis D.
Statistics in Medicine 2017 Epub 2017 Aug 6